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Scientist

 Person

Dr Amsha Ramburan

 

 Telephone

 0312402650

 Email

amusha.ramburan@nhls.ac.za

Campus

IALCH

Designation

Scientist

Academic Qualifications

Studied at the University of Natal completing B.Med.Sci, B.Med.Sci (Hons) and an M.Med.Sci (Anatomical Pathology). Masters degree, supervised by Prof D Govender, was a molecular and immunohistochemical investigation of cell adhesion molecules in a cohort of 140 nephroblastomas. Joined the Medical Research Council (MRC) in May 2004 as a Research Intern based at the Centre for Molecular and Cellular Biology, Department of Medical Biochemistry, University of Stellenbosch. Embarked on a PhD in 2005, supervised by Prof JC Moolman-Smook, investigating the N-terminal interactors of cardiac myosin-binding protein C (cMyBPC) under various phosphorylation conditions. Graduated December 2008 with a PhD and joined the Department of Anatomical Pathology as a scientist in February 2009. ResearchGate Profile

 List of Publications
  1. Ramdial PK, Sing Y, Ramburan A, Naidu TK, Samuel EY, Bagratee JS, Calonje E. Infantile donovanosis presenting as external auditory canal polyps: a diagnostic trap. Am J Dermatopathol. 2012 Dec;34(8):818-21
  2. Ramdial PK, Sing Y, Ramburan A, Dlova NC, Bagratee JS, Calonje E. Bartonella quintana-induced vulval bacillary angiomatosis. Int J Gynecol Pathol. 2012 Jul;31(4):390-4
  3. Uys GM, Ramburan A, Loos B, Kinnear CJ, Korkie LJ, Mouton J, Riedemann J, Moolman-Smook JC. Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C. BMC Cell Biol. 2011 May;12:18.
  4. Ramburan A, Korkie LJ and Moolman-Smook JC. Cardiac myosin binding protein C, adrenergic stimulation and cardiac contractility. SA Heart. 2010 7(1): 38-47
  5. Ramdial PK, Sing Y, Subrayan S, Calonje E, Aboobaker J, Sydney C, Sookdeo D, Ramburan A, Madiba TE. Granulomas in acquired immunodeficiency syndrome-associated cutaneous Kaposi sarcoma: evidence for a role for Mycobacterium tuberculosis. J Cutan Pathol. 2010 Aug;37(8):827-34.
  6. Ramburan A, Hadley GP, Govender D. The immunoexpression of E-cadherin, cadherin-11, a-, b, and g-catenins in nephroblastomas. Pathology. 2006 Feb;38(1):39-44.
  7. Ramburan A, Oladiran F, Smith CA, Hadley GP, Govender D. Microsatellite analysis of the Adenomatous Polyposis Coli (APC) gene and immunoexpression of b-catenin in nephroblastomas: a study including 83 cases treated with preoperative chemotherapy. J Clin Pathol 2005; 58(1):44-50.
  8. Naidoo R, Ramburan A, Reddi A and Chetty R. Aberrations in the DNA repair genes and the clinical impact on oesophageal squamous carcinomas from high incidence areas in South Africa. J Clin Pathol. 2005 Mar;58(3):281-4.
  9. Ramburan A, Chetty R, Hadley GP, Naidoo R, Govender D. Microsatellite analysis of the DCC gene in nephroblastomas: Pathologic correlations and prognostic implications. Mod Pathol 2004; 17:89-95.
  10. Ramburan A, Govender D. Cadherins and catenins in pathology. Curr Diagn Pathol 2002; 8:305-317.

In Press:

Sing Y, Ramdial PK, Ramburan A, Sewram V.  Cytokeratin expression in gastrointestinal stromal tumors:  Morphology, meaning, and mimicry.  Ind J Pathol Microbiol.


CONFERENCE PRESENTATIONS

  1. Ramburan A, Korkie L, Loos B and JC Moolman-Smook. Novel interactors: additional functions of N-terminal cardiac myosin-binding protein C? South African Heart Congress, Wild Coast Sun, 2-5 November 2008.
  2. Ramburan A, Korkie L and JC Moolman-Smook. Trisphosphorylation of cMyBPC and its relation to the energy compromise hypothesis in hypertrophic cardiomyopathy. South African Society for Biochemistry and Molecular Biology. University of KwaZulu-Natal, July 2006.
  1. Ramburan A, Korkie L and JC Moolman-Smook. Trisphosphorylation of cMyBPC and its relation to the energy compromise hypothesis in hypertrophic cardiomyopathy. AstraZeneca Research Day. University of the Western Cape, 25th of October 2005.
  2. Ramburan A and JC Moolman-Smook. PCR-mediated homologous recombination- simplified construct generation. University of Stellenbosch Academic Year Day, 17th-18th August 2005.
  3. Ramburan A, Hadley GP, Govender D. The immunoexpression of E-cadherin, a-, b-, and g-catenins in nephroblastomas. The 43rd Annual Congress of the Federation of South African Societies of Pathology, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, 28th June-2nd July 2003.
  4. Ramburan A, Chetty R, Hadley GP, Naidoo R, Govender D. An investigation of the DCC gene in nephroblastomas. The 42nd Annual Congress of the Federation of South African Societies of Pathology, Faculty of Health Sciences, University of the Free State, Bloemfontein, 1-4th July 2002.
  5. Ramburan A, Chetty R, Hadley GP, Naidoo R, Govender D. An investigation of the DCC gene in nephroblastomas. Faculty Research Day, Nelson R. Mandela School of Medicine, University of Natal, Durban, 18 September 2002.

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